[gov3009-l] Applied Statistics 3/22/17 - Elizabeth Stuart

Ban, Pamela pban at fas.harvard.edu
Mon Mar 20 10:20:23 EDT 2017

Hi all,

This week at the Applied Statistics workshop we will be welcoming Elizabeth Stuart, a Professor and Associate Dean for Education at Johns Hopkins School of Public Health.  She will be presenting work entitled "Estimating population effects: Assessing and enhancing the generalizability of randomized trials to target populations."  Please find the abstract below and on the website.

We will meet in CGIS Knafel Room 354 at noon and lunch will be provided.


Title: Estimating population effects: Assessing and enhancing the generalizability of randomized trials to target populations

Abstract: With increasing attention being paid to the relevance of studies for real-world practice (such as in education, international development, and comparative effectiveness research), there is also growing interest in external validity and assessing whether the results seen in randomized trials would hold in target populations. While randomized trials yield unbiased estimates of the effects of interventions in the sample of individuals (or physician practices or schools) in the trial, they do not necessarily inform about what the effects would be in some other, potentially somewhat different, population.  While there has been increasing discussion of this limitation of traditional trials, relatively little statistical work has been done developing methods to assess or enhance the external validity of randomized trial results.  This talk will first provide empirical data on the potential size of external validity bias in education research.  It will then discuss design and analysis methods for assessing and increasing external validity, as well as general issues that need to be considered when thinking about external validity.  The primary analysis approach discussed will be a reweighting approach that equates the sample and target population on a set of observed characteristics.  Underlying assumptions, performance in simulations, and limitations will be discussed.  Implications for how future studies should be designed (and what data needs to be collected) in order to enhance the ability to assess generalizability will also be discussed.

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